Principles and Applications of Optical Coherence Tomography

Level: Advanced Length: 4 hours Format: In-Person Lecture Intended Audience: This material is appropriate for scientists, engineers, and clinicians who are performing research in medical imaging. Description: Optical coherence tomography (OCT) is a new imaging modality, which is the optical analog of ultrasound. OCT can perform high resolution cross sectional imaging of the internal structure of biological tissues and materials. OCT is promising for biomedical imaging because it functions as a type of optical biopsy, enabling tissue pathology to be imaged in situ and in real time. This technology also has numerous applications in other fields ranging from nondestructive evaluation of materials to optical data storage. This course describes OCT and the integrated disciplines including fiber optics, interferometry, high-speed optical detection, biomedical imaging, in vitro and in vivo studies, and clinical medicine Learning Outcomes: This course will enable you to: - describe OCT imaging devices such as microscopes, hand held probes and catheters - provide an overview of clinical imaging including clinical ophthalmology, surgical guidance, and detection of neoplasia and guiding biopsy - explain a systems viewpoint of OCT technology - discuss transitioning technology from the laboratory to the clinic - describe the principles of optical coherence tomography (OCT) - describe ultrafast laser technology and other low coherence light sources - gain an overview of materials applications - describe OCT detection approaches and factors governing performance - describe functional imaging such as Doppler and spectroscopic OCT Instructor(s): James G. Fujimoto is Elihu Thomson Professor of Electrical Engineering at MIT, visiting professor of ophthalmology at Tufts University School of Medicine, and adjunct professor at the Medical University of Vienna. His group and collaborators were responsible for the invention and development of optical coherence tomography (OCT), performing some of the first studies in ophthalmology. He was a cofounder of the startup company Advanced Ophthalmic Devices, which developed ophthalmic OCT and was acquired by Carl Zeiss and LightLab Imaging, which developed cardiovascular OCT and was acquired by Goodman, Ltd. Dr. Fujimoto published over 500 peer-reviewed journal articles and coedited 13 books. Dr. Fujimoto has honorary doctorates from the Nicolaus Copernicus University in Poland and the Friedrich Alexander University of Erlangen-Nuremberg and is a member of the National Academy of Engineering, National Academy of Sciences, and American Academy of Arts and Sciences. Event: SPIE Photonics West 2015 Course Held: 8 February 2015